Activer le mode plus accessible
Passer au contenu principal
Désactiver le mode plus accessible
FACULTIES and SCHOOLS
UMONS in CHARLEROI
Anatomy and Cell Biology
General, Organic and Biomedical Chemistry
Human Biology and Toxicology
Laboratory of Pharmaceutical Analysis
Physiology and Pharmacology
Therapeutic Chemistry and Pharmacognosy
Tous les sites
Ce site : Neuroscience
Faculties and Schools
Faculty of Medicine and Pharmacy
Teaching and Research Units
Head of Unit:
University of Mons
“Pentagone” wing 1A
Avenue du Champ de Mars 6
B - 7000 MONS (BELGIUM)
Neuroscience research scientists currently agree that memory is stored in our brain thanks to synapses adjusting their effectiveness to modify neuronal selectivity. Synapses are junctions which link brain cells into a neuronal network;
It is possible to start a durable increase in synaptic effectiveness (during several hours) on 0.5 mm thick brain slices (hippocampus), kept alive artificially. This phenomenon is known as long-term potentiation (abbreviated to LTP). LTP thus constitutes a model of elementary memory which can be studied in vitro. These are the two characteristics that make it fascinating to research;
The mechanisms which trigger the release of LTP and keep it in its initial phase (first hour) are well-known. However, mechanisms responsible for its longer-term maintenance (in particular from 1 to 4 hours after its induction) are yet unknown;
We are currently focusing on the mechanisms of the more durable phase of the LTP (L-LTP or Late Long-Term Potentiation)
We also study neuropathologies inducing alterations in memory formation and in long term synaptic plasticity such as alzheimer's disease, multiple sclerosis, traumatic brain injury and post-traumatic stress disorder.
Research Institute for Biosciences: collaborative project to study the impact of neuroinflammation induced by a mechanical stress in novel in vitro models.
Institute of Neurosciences (IoNS) of UCL: collaborative project on alzheimer's disease.
Kings College London: collaboration to study the role of CaMKII alpha on synaptic plasticity and memory.
20, place du Parc, B7000 Mons - Belgium
Phone: +32 (0)65 373111